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24November/ December2009 ChromatographyTodayisdistributedfreeofchargetoscientists, laboratorytechniciansandenvironmentaliststhroughoutthe UnitedKingdom. Thepublicationhasthesupportofleadingsuppliersof equipmentintheregionandisdisplayedatthemajorexhibitions andconferencesinthesemarketstoattractadditionalreadership. ChromatographyTodayispublishedwiththefullsupportofthe ChromatographicSociety. Telephone:+ 44( 0) 1727731819 chromatographytoday@ ilmdesigns. co. uk www. chromatographytoday. com Volume1Issue1. December2007 WhatistheBestWaytoAchieve HighResolutionChromatography? Micro- SolidPhaseExtractionin thePharmaceuticalIndustry. DoSub2µmParticlesOfferTheBest PerformanceForHighThroughputScreening? Inthisissue: Volume1Issue2. February2008 GelPermeationChromatography UnderExtremeConditions AchievingHighHPLCPerformanceatModerate PressuresusingFused- Core T ParticleTechnology UHPLCWhyallthehype? Inthisissue: OrthogonalDetectionHelpsValidateControl StrategyforLate- StageCompoundDevelopment Preview- TheChromatographicSociety'sSpringSymposium andAnnualGeneralMeeting, MadejskiStadium, Reading Review- BiGPrep4 ChromatographicSociety'sSymposiumforSmall andLargeScalePrepHPLC Volume1Issue3. June2008 IndustrialTraining& ContinuingProfessionalDevelopment forAnalyticalChemists ProtienAnalysisusingProteotypicPeptidesandLC- MS ChargedAerosolDetection Inthisissue: ANovelApproachtoMeasurementofHydrodynamic RadiusforaStandardProteinUsingUVAreaDetection NanoQuantityAnalyseDetector( NQADTM) ANewAlternativeinSensitiveHPLCDetection Advertiseinour nextissue... Volume1Issue4. September/ October2008 AFullyAutomatedProcedureforthePreparationand AnalysisofFattyAcidMethylEsters Superheatedwaterchromatography- ahottopicforLCandLC- MS AnalysisofMacacaporanga( Anibaparviflora) Leaf EssentialOilbyUsingComprehensive Inthisissue: AdvancesinStationaryPhasesforLiquidChromatography GC- IRDAnalysisofRegioisomericSubstitutedPhenethylamines ofMassSpectralEquivalence HighPerformanceCountercurrentChromatography( HPCCC) finally allowstheadvantagesofliquid/ liquidchromatography Two- dimensionalGasChromatographyCombinedwith Rapid- ScanningQuadrupoleMassSpectrometry EvaluationofanewDynamicBackgroundCompensationAlgorithmfor ImprovingAromaCharacterisationbyThermalDesorption- GC- MS Volume2Issue3. September2009 Inthisissue: ThePursuitofChiralAnionExchange- TypeSelectors: FromConcepttoApplication TheImportanceofChiralSeparationsinSingleEnantiomerPatentCases ChiralMethodDevelopment ScreeningTechniques: ApracticalguideandnewapproachesinLC- MS TurbulentFlowChromatography: anEvolvingSolutionforBioanalysis ReversedPhaseChiralMethodDevelopmentUsing Polysaccharide- basedStationaryPhases InSearchofaGeneric ChiralStrategy: 101SeparationsWithOneMethod Reporton2009SpringSymposiumoftheChromatographicSociety ModernChiralSeparationsusingHPLCandSFCforMethod DevelopmentandPrepPurification HPLC2009- 34thInternationalSymposiumonHigh- Performance LiquidPhaseSeparationsandRelatedTechniques Volume2Issue4. November/ December2009 Inthisissue: PreparativeChiralSeparations- fromLaboratoryScaletoProduction Enablingfacile, rapidandsuccessfulchromatographicFlashpurification ApplicationsofLiquid- LiquidChromatographyInstrumentationfor LaboratoryPreparative& ProcessChemistry TheChromatographicSociety2010 PresentationtoLindner ValveInnovationOptimisesChromatographyProcess; RemovingDeadLegs, MinimisingHold- UpVolumes& IncreasingYields TheJohnDolphinFellowships Facingthechallengesinbio- pharmaceuticalproduction: developmentsinionexchangemediatobringdowncostofgoods. The18thInternationalReidBioanalyticalForum 25 ! " # $ % & ' & ( ) * + ' , - . ) / % - 0 / ' + ' 1 ' 2 . - 3 - . 4 MORESEPARATINGPOWER IntroducingaC18withExtraResolvingPower ACEC18- AR 5 6 7 $ 1 / 8 % + ! " # ! $ % & ! ' ( " ! ) * $ ' ( + , & * - & . ( $ * . $ / # ! , . * , 0 ' - $ ! 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MagicNetBasicsoftwareoffersanintuitive interfacebetweentheuserandtheinstrumentwhichensuresthatthepathfromsample analysistoreportedresulthasneverbeensimpler. In- houseSwissdevelopment, manufactureandqualitycontrolmeansMetrohmoffersathreeyear instrumentwarrantyandtenyearsuppressorwarrantyasstandard. AtMetrohmwefirmlybelieve thatthequalityandexperienceofourpeoplealongwiththeinstrumentsdifferentiateourselves fromthecompetition. WeofferateamofUKbasedtechnicalsupportthatgoesmuchfurther productfamiliarizationandincludeoptimizationoftheapplicationaspartoftheserviceweoffer. Ourcustomer'sinformusthattheyliketheflexibilityandeaseofaccessofallhardware componentswithMetrohmIntelligentIC. Whatthismeansisthatwithasimplechangeof separationcolumnandeluentonecanchangethechemistryofanalysis. Ifthenumberof samplestobeassayedorbudgetconstraintspreventstheoptionofdualsystems; withthe883 BasicICplusonecanrunaniondeterminationsinthemorningfollowedbythecationanalysis afterlunch. 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